A customer asks: do you integrate with our EHR?
Scope the connection to Epic, Oracle Health, athenahealth, eClinicalWorks, NextGen or MEDITECH, then build and run it.
EHR integration services →Healthcare interoperability company
We engineer the connections between EHRs, payers, labs, pharmacies, devices and your product: FHIR R4 APIs, HL7 v2 interfaces, X12 EDI, C-CDA and DICOM, built to CMS-0057-F, TEFCA and ONC rules. Use this page as the map of every interoperability service and guide we publish.
For healthcare software companies, payers, provider organizations and health IT teams in the US, with ABDM work for India.
The short answer
Healthcare interoperability is the ability of separate systems to exchange data and use it without manual re-entry. In practice that means four layers: transport and APIs (FHIR REST, HL7 v2 over MLLP, X12 over a clearinghouse, Direct and document exchange), shared content standards (US Core and USCDI, C-CDA, NCPDP SCRIPT, DICOM), terminology (LOINC, SNOMED CT, RxNorm, ICD-10-CM, CPT) and the operating layer that keeps interfaces running (engines, monitoring, identity matching, consent). Interoperability solutions are the engineering, platforms and support that make those layers work for a specific workflow, such as getting lab results into your app, answering a payer prior authorization in FHIR, or joining a TEFCA network.
Buyer paths
Start from what is blocking you. Each path goes to the page that owns that job.
Scope the connection to Epic, Oracle Health, athenahealth, eClinicalWorks, NextGen or MEDITECH, then build and run it.
EHR integration services →Decide what to standardize, where vendor adapters sit, and whether an aggregator belongs in the design.
Multi-EHR integration architecture →Build the Patient Access, Provider Access, Payer-to-Payer and Prior Authorization APIs that CMS-0057-F requires.
CMS-0057-F implementation →Stabilize, migrate or extend interfaces on Mirth Connect, Rhapsody, Cloverleaf or Corepoint.
HL7 integration services →Connect 270/271, 276/277, 278, 837 and 835 through your clearinghouse with reconciliation built in.
X12 EDI integration →Query and exchange through HIEs, Carequality, CommonWell and TEFCA QHINs with consent handled correctly.
TEFCA and QHIN connectivity →Services and guides
Every interoperability service we deliver, grouped the way buyers search for them.
Vendor access programs, APIs and customer go-live.
Pick the standard by the job, not by fashion.
The rules that set deadlines for interoperability work.
Build on the engine you have, or move to a better one.
The data flows around the chart.
Standards
Most programs combine several of these. The table shows what each carries and where it is required.
| Standard | What it carries | Where you meet it |
|---|---|---|
| FHIR R4 (US Core, SMART, Bulk Data) | Resources such as Patient, Observation and Claim over REST and OAuth 2.0 | ONC (g)(10) certified EHR APIs, CMS-0057-F payer APIs, patient apps |
| HL7 v2.x | Event messages: ADT, ORM, ORU, SIU, MDM, DFT over MLLP | Hospital feeds, labs, radiology, charges |
| X12 5010 EDI | 270/271, 276/277, 278, 837P/I/D, 835, 999 and 277CA | HIPAA-mandated claims, eligibility and remittance |
| C-CDA R2.1 | Clinical documents such as CCD and Discharge Summary | Transitions of care, Carequality, CommonWell, Direct |
| DICOM and DICOMweb | Images and imaging metadata | PACS, radiology and cardiology systems |
| NCPDP SCRIPT and Telecommunication | Prescriptions, renewals and pharmacy claims | E-prescribing through Surescripts and pharmacy benefit claims |
Regulations
Dates come from the final rules. We build to the requirement and to the implementation guides named in each rule.
Medicare Advantage, Medicaid and CHIP payers must meet prior authorization decision timeframes (72 hours expedited, 7 calendar days standard) from January 1, 2026. Impacted payers, including QHP issuers on the federal exchanges, must run the Provider Access, Payer-to-Payer and Prior Authorization APIs by January 1, 2027.
Certified health IT moves to USCDI v3 as the baseline data standard from January 1, 2026, alongside the (g)(10) standardized FHIR API criterion.
The 21st Century Cures Act lets HHS OIG fine developers and exchanges up to $1 million per violation, and providers face disincentives under the 2024 rule.
Qualified Health Information Networks exchange under the Common Agreement, with FHIR-based exchange being phased in alongside document query.
Buyer decision
Healthcare interoperability vendors fall into four groups. Most organizations use two of them together.
| Approach | Best when | Trade-off |
|---|---|---|
| Build in-house | Integration is core to your product and you can hire FHIR, HL7 and X12 specialists | Slow first launch while the team learns vendor programs and customer IT processes |
| Interface engine (Mirth, Rhapsody, Cloverleaf, Corepoint) | Many HL7 v2 feeds inside a health system or lab | Needs engine specialists; licensing changed for Mirth Connect 4.6 |
| Integration platform or aggregator | Reaching many EHR sites quickly for read-heavy use cases | Per-connection pricing and less control over write-back |
| Interoperability engineering partner (Nirmitee) | You need production connections now and want to own the code, mappings and runbooks | Needs a named product owner on your side for workflow decisions |
Delivery phases
1 to 2 weeks: systems, workflows, standards, access and owners agreed in writing.
Vendor program registration, customer interface requests, data mapping and test plan.
Connectors, mappings and error handling tested against sandboxes and customer test systems.
Cutover with rollback criteria, then monitoring and support, or a full handover.
Each EHR, payer or lab adds an adapter; each customer site adds configuration and testing.
Read-only is lighter than write-back, which needs clinical sign-off and partner-level access.
FHIR plus HL7 v2 plus X12 means three test and monitoring surfaces.
CMS-0057-F or TEFCA dates can require parallel workstreams.
Backfills and migrations add reconciliation and validation work.
Handover to your team, or managed monitoring with on-call support.
Delivered work
Client names are withheld; each is a real engagement. Our open-source work is public on GitHub.
FHIR prior authorization servers for the CMS-0057-F workflow, tested with the Inferno test kits and published on GitHub.
Passed 47 of 47 ONC (g)(10) SMART App Launch tests in Inferno on 11 June 2026.
Claim validation, 999 and 277CA acknowledgement handling and 835 remittance reconciliation for a behavioral health EHR.
A referral and tumour-board exchange across a regional hospital network, where each record stays at its source hospital.
Readings from connected devices captured offline and reconciled with the central record when the network returns.
Scheduling, charts, care plans and billing on a FHIR server as the only backend, with single sign-on through OAuth token exchange.
Healthcare interoperability solutions are the software, platforms and engineering services that let separate health systems exchange data and use it. They include FHIR APIs, HL7 v2 interfaces, X12 EDI, document exchange, integration engines, terminology mapping, identity matching and the monitoring that keeps interfaces running.
HIMSS describes four levels: foundational (systems can send and receive data), structural (the format is standard, such as HL7 v2 or FHIR), semantic (the meaning is shared through code systems like LOINC and SNOMED CT) and organizational (governance, consent and policy that let organizations trust the exchange).
FHIR R4 with US Core and SMART App Launch for APIs, HL7 v2 for hospital event feeds, X12 5010 for claims and eligibility, C-CDA for clinical documents, DICOM for imaging and NCPDP SCRIPT for e-prescribing. USCDI v3 defines the minimum data set certified EHRs must exchange.
Match the vendor to the job. Interface engines suit many HL7 v2 feeds, aggregators suit fast read access across many EHR sites, and an engineering partner suits production connections you want to own. Ask for public evidence such as Inferno test results or open-source code, a signed BAA, and who runs the interfaces after go-live.
A healthcare interoperability platform is software that hosts connectors, transforms data between standards, routes messages and monitors delivery. Examples range from interface engines such as Mirth Connect and Rhapsody to API platforms. Interoply is our platform for running the integrations we build.
CMS-0057-F requires Medicare Advantage organizations, Medicaid and CHIP programs and QHP issuers on the federal exchanges to run Provider Access, Payer-to-Payer and Prior Authorization FHIR APIs, plus an enhanced Patient Access API, by January 1, 2027. Medicare Advantage, Medicaid and CHIP payers must also meet new prior authorization decision timeframes from January 1, 2026.
TEFCA is the national framework for exchange between Qualified Health Information Networks under a Common Agreement. You join through a QHIN, directly or as a participant of one. It matters if you need records from outside your network or must answer treatment and individual access queries.
Information blocking is a practice by a provider, health IT developer or exchange that is likely to interfere with access, exchange or use of electronic health information, unless an exception applies. The 21st Century Cures Act defines it, and HHS enforces it with fines for developers and exchanges and disincentives for providers.
HL7 v2 is an event-message standard from the 1980s and 1990s that still carries most hospital feeds. FHIR is HL7's modern API standard built on REST, JSON and OAuth 2.0. Most interoperability programs use both, with FHIR for apps and APIs and HL7 v2 for real-time hospital events.
Cost depends on the number of systems and sites, read-only versus write-back, the standards in scope, compliance deadlines, data history and whether we run the interfaces after go-live. We scope a fixed first phase after discovery instead of quoting a list price.
We sign Business Associate Agreements and are ISO 27001:2022 certified. Connections use least-privilege access, encryption in transit and at rest, audit logs of every exchange and synthetic data in development.
Yes. We build and support interfaces on Mirth Connect, Rhapsody, Infor Cloverleaf and Corepoint, work with Redox, and plan migrations between engines, including moves driven by the Mirth Connect 4.6 license change.
Start the conversation
Tell us the systems, the workflow and the deadline. We reply with the standards involved, the access you will need and a first milestone.
A systems list and a de-identified example are enough. No patient records or credentials.
The final rules and standards behind the dates and requirements on this page.